Please note that carrier genes do not result in disease. It takes double genes for the dog to be affected.

DM - ENGLISH & FRENCH BULLDOGS

Degenerative myelopathy (DM) is a progressive disease of the spinal cord in older dogs, onset typically between 8 and 14 years of age.

It begins with a loss of coordination (ataxia) in the hind limbs. The affected dog will wobble when walking, knuckle over or drag the feet. As the disease progresses, the dog's hind legs will weaken and eventually the dog will be unable to walk at all, and can experience loss of urinary and fecal continence with eventual weakness in the front limbs. Fortunately, there is no direct pain associated with Degenerative Myelopathy.

A small percentage of dogs that have inherited two copies of the mutation will not experience symptoms at all. Thus, this disease is not completely penetrant, meaning the disease does not affect every dog that has the genotype.

Ethical breeding practices with this disorder:

• No restrictions on cleared dogs.

• No restrictions with a cleared to a carrier dog. If the dog you’re breeding is a carrier, it is a must to test the intended mate to be cleared.

• Restriction on breeding two carriers.

• Restriction on breeding fully affected (two copies of the variant) to a carrier. Intended mates to fully affected should be cleared.

HUU - English & French Bulldogs

The Hyperuricosuria mutation is autosomal recessive. Both parents will need to be carriers of the mutation to pass it onto their offspring. Only individuals that have two copies of the mutation, have a higher risk of developing clinical signs of the disease. Carriers of only one copy of the mutation will not develop the disease.

Dogs with this genetic mutation metabolize waste products as uric acid in their urine, this condition that predisposes dogs to bladder stones that can result in urinary obstruction. The uric acid forms into hard stones in the bladder, causing pain and inflammation as the stone moves through the urinary tract.

A dog that has difficulty urinating or appears to have an inflamed bladder may have HUU. Other signs can include blood in the urine and frequent urination. If the dog is unable to pass the urate stones without medical intervention, surgery is required to remove them. If the urinary tract is blocked, the condition can be life threatening. HUU is uncomfortable and painful for the dog.

Carriers will not show any symptoms of HUU. Affected dogs may not show any signs, so it is important to test dogs for HUU prior to breeding.

Ethical breeding practices with this disorder:

• No restrictions on cleared dogs.

• No restrictions with a cleared to a carrier dog. If the dog you’re breeding is a carrier, it is a must to test the intended mate to be cleared.

• Restriction on breeding two carriers.

• Restriction on breeding fully affected (two copies of the variant) to a carrier. Intended mates to fully affected should be cleared.

CMR1 - English & French Bulldogs

Canine Multifocal Retinopathy (CMR), a recessive eye disorder, is known to affect several breeds including the English Bulldog. This causes raised lesions that form on the retina and alters the appearance of the eye but usually does not affect sight. These lesions, looking somewhat like blisters, vary in location and size. Typically they are present in both eyes of the affected dog. Lesions may disappear, or may result in minor retinal folding. Symptoms usually appear when a puppy is only a few months old, and generally do not worsen over time.

Since CMR1 is recessive, both parents would need to be carriers of the mutation to produce an affected puppy. Breeding two unaffected or one unaffected and one carrier will not produce affected offspring. However, if one parent is a carrier, a percentage of the offspring will be carriers. It is necessary to test for the presence of the CMR mutation before breeding, so as not to breed two carriers together, and unwittingly produce a fully affected puppy. Dogs have two copies of the mutation are susceptible to develop retinal deformation, although fully affected dogs do not always develop into disease.

In most cases, treatment is not required.

Ethical breeding practices with this disorder:

• No restrictions on cleared dogs.

• No restrictions with a cleared to a carrier dog. If the dog you’re breeding is a carrier, it is a must to test the intended mate to be cleared.

• Restriction on breeding two carriers.

• Restriction on breeding fully affected (two copies of the variant) to a carrier. Intended mates to fully affected should be cleared.

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Bulldogs by far have the most personality out of any breed. That being said, they make great companions! It's hard to only want one! Once you have owned a bulldog, you'll never go back!

All of our pups come from health-tested parents to produce healthy pups.

Our puppies start at $3,000 USD and up based on bloodline, structure, color and gender.

NOTE: Your puppy is not reserved until your deposit is secured.

The paperwork we gave you upon meeting up is already signed by us, to transfer ownership to the new owners. You will have to fill out all the information and send the paperwork & a photo of your new puppy to AKC at the following address.

The American Kennel Club

8051 Arco Corporate Drive, Suite 100

Raleigh, NC 27617-3390

You may also do this online by sending a photos of the filled out application and a photo of your puppy to the following email.

registrationdept@akc.org

Be advised you can do the registration process on the AKC website but we recommend sending a photo to AKC so you could get the correct dog’s color on their registration, the website only shows you the standard colors.